Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795764 | 1.00 | ACP1 (0.33) | ACP1TRPA1MEN1KMT2ACES2 | |
| SCHEMBL11072430 | 1.00 | ACP1 (0.33) | ACP1TRPA1MEN1KMT2ACES2 | |
| SCHEMBL11280822 | 1.00 | ACP1 (0.33) | ACP1TRPA1MEN1KMT2ACES2 | |
| SCHEMBL11280837 | 1.00 | ACP1 (0.33) | ACP1TRPA1MEN1KMT2ACES2 | |
| SCHEMBL10799560 | 0.79 | TSHR (0.34) | ACP1TRPA1MEN1KMT2ACES2 | |
| SCHEMBL10795597 | 0.74 | TSHR (0.33) | MEN1KMT2ACES2BCHECES1 | |
| SCHEMBL10795586 | 0.73 | TSHR (0.57) | ACP1TRPA1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11069993 | 0.72 | TSHR (0.56) | ACP1MEN1KMT2ALMNAHTT | |
| SCHEMBL10800156 | 0.71 | TSHR (0.52) | MEN1KMT2ALMNAHTTTSHR | |
| SCHEMBL14540610 | 0.64 | TSHR (0.43) | ACP1MEN1KMT2AHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489078-A | Diazaheterocyclopurines used as anti-broncho spasmatics and vasodilators | MEAD JOHNSON & COMPANY (US) | 1984-12-18 | — | — | US | claimed |
| US-4366156-A | Antiallergic methods using diazaheterocyclopurines | MEAD JOHNSON & COMPANY (US) | 1982-12-28 | — | — | US | claimed |
| US-4298734-A | PHOSPHODIESTERASE INHIBITORS, BRONCHODILATORS, PERIPHERAL VASODILATORS | MEAD JOHNSON & COMPANY (US) | 1981-11-03 | — | — | US | claimed |