Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067219 | 0.90 | HTR1D (0.38) | KCNN4HTR1DHTR1BDRD2DRD3 | |
| SCHEMBL11070194 | 0.89 | HTR1D (0.37) | HTR1DHTR1BDRD2DRD3HTR1A | |
| SCHEMBL11076146 | 0.88 | HTR1D (0.36) | HTR1DHTR1BDRD2DRD3HTR1A | |
| SCHEMBL11068797 | 0.87 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL11072605 | 0.85 | SLC6A4 (0.41) | KCNN4 | |
| SCHEMBL11075429 | 0.84 | HTR1D (0.34) | HTR1DHTR1BDRD2DRD3HTR1A | |
| SCHEMBL11075507 | 0.84 | HTR1D (0.39) | HTR1DHTR1BDRD2DRD3HTR1A | |
| SCHEMBL11078545 | 0.81 | KCNN4 (0.33) | KCNN4CRHR1 | |
| SCHEMBL11073938 | 0.81 | GRIN2B (0.37) | KCNN4 | |
| SCHEMBL11077331 | 0.78 | KCNN4 (0.35) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |