Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 2/20 | 0.43 |
| ▸ | SELE | P16581 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935000 | 0.82 | SELP (0.49) | SELPSELEHPSEADRB2ADRB3 | |
| SCHEMBL11065554 | 0.81 | PPARA (0.50) | PPARGPPARA | |
| SCHEMBL11065557 | 0.81 | PPARA (0.50) | PPARGPPARA | |
| SCHEMBL11306547 | 0.81 | HDAC11 (0.51) | SELPSELEHPSEADRB2ADRB3 | |
| SCHEMBL11073287 | 0.80 | HPSE (0.52) | SELPSELEHPSEADRB2ADRB3 | |
| SCHEMBL5534461 | 0.79 | SELP (0.48) | SELPSELEHPSEADRB2ADRB3 | |
| SCHEMBL11306397 | 0.77 | FFAR1 (0.43) | NR1H4ABCC4MAPTKDM4ERAB9A | |
| SCHEMBL11306400 | 0.77 | FFAR1 (0.43) | NR1H4ABCC4MAPTKDM4ERAB9A | |
| SCHEMBL5523734 | 0.76 | SELP (0.50) | SELPSELEHPSEADRB2ADRB3 | |
| SCHEMBL11067526 | 0.75 | AKR1C3 (0.51) | KDM4ENPC1RAB9APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |