Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 0.80 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 0.80 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-648051 SCHEMBL157166 | 0.89 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| L-648051 SCHEMBL30997207 | 0.88 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL9735766 | 0.86 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL9733439 | 0.85 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL9734027 | 0.85 | CYSLTR2 (0.91) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL9733653 | 0.84 | CYSLTR2 (0.75) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL10772382 | 0.84 | CYSLTR2 (0.74) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL11073023 | 0.83 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL9733378 | 0.83 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 | |
| SCHEMBL11073013 | 0.81 | CYSLTR1 (0.56) | CYSLTR2CYSLTR1GRM2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104885-A1 | Leukotriene antagonists, their production, and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-04-04 | — | — | EP | claimed |