Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889556 | 1.00 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL7786670 | 0.93 | — | — | |
| SCHEMBL14478078 | 0.93 | TSHR (0.47) | TSHRLMNATHRBALDH1A1MEN1 | |
| SCHEMBL17675883 | 0.93 | — | — | |
| SCHEMBL10457162 | 0.89 | — | — | |
| SCHEMBL22062482 | 0.89 | — | — | |
| SCHEMBL30054741 | 0.89 | TSHR (0.53) | TSHRLMNATHRBALDH1A1MEN1 | |
| SCHEMBL14660138 | 0.88 | TSHR (0.50) | TSHRLMNATHRBALDH1A1MEN1 | |
| SCHEMBL14660139 | 0.88 | TSHR (0.50) | TSHRLMNATHRBALDH1A1MEN1 | |
| SCHEMBL14478077 | 0.85 | TSHR (0.57) | TSHRLMNATHRBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450303-A | IN PRESENCE OF OXYGEN AND SAMARIN SALT | PHILLIPS PETROLEUM COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| EP-0099572-A1 | Disproportionation of functional olefins | PHILLIPS PETROLEUM COMPANY (US) | 1984-02-01 | — | — | EP | disclosed |
| US-4282383-A | FREE RADICAL CATALYST; TERTIARY-BUTYL, CUMENE OR P-DIISOPROPYLBENZENE HYDROPEROXIDE | THE UPJOHN COMPANY (US) | 1981-08-04 | — | — | US | disclosed |