Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073503 | 1.00 | TLR7 (0.39) | TLR7LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11073524 | 0.90 | TLR7 (0.39) | TLR7LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11073526 | 0.90 | TLR7 (0.39) | TLR7LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11074223 | 0.90 | TLR7 (0.40) | TLR7LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11074226 | 0.90 | TLR7 (0.40) | TLR7LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11069973 | 0.87 | TLR7 (0.39) | TLR7LMNANPSR1GPBAR1 | |
| SCHEMBL11069971 | 0.87 | TLR7 (0.39) | TLR7LMNANPSR1GPBAR1 | |
| SCHEMBL11079005 | 0.84 | TLR8 (0.41) | TLR7LMNANPSR1TLR8 | |
| SCHEMBL11079027 | 0.84 | TLR8 (0.41) | TLR7LMNANPSR1TLR8 | |
| SCHEMBL11072598 | 0.83 | GPBAR1 (0.38) | TLR7LMNAHTTNPSR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |