Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073605 | 1.00 | EPHX2 (0.48) | EPHX2TDP1P2RY1TRPV1L3MBTL1 | |
| SCHEMBL11073540 | 0.89 | MAPT (0.48) | EPHX2TDP1P2RY1TRPV1L3MBTL1 | |
| SCHEMBL11073541 | 0.89 | MAPT (0.48) | EPHX2TDP1P2RY1TRPV1L3MBTL1 | |
| SCHEMBL11076936 | 0.89 | EPHX2 (0.44) | EPHX2TDP1P2RY1TRPV1L3MBTL1 | |
| SCHEMBL11076920 | 0.89 | EPHX2 (0.44) | EPHX2TDP1P2RY1TRPV1L3MBTL1 | |
| SCHEMBL11079910 | 0.86 | TDP1 (0.61) | EPHX2TDP1TRPV1L3MBTL1HPGD | |
| SCHEMBL11079907 | 0.86 | TDP1 (0.61) | EPHX2TDP1TRPV1L3MBTL1HPGD | |
| SCHEMBL11079418 | 0.81 | EPHX2 (0.50) | EPHX2TDP1TRPV1L3MBTL1HPGD | |
| SCHEMBL11079419 | 0.81 | EPHX2 (0.50) | EPHX2TDP1TRPV1L3MBTL1HPGD | |
| SCHEMBL11072580 | 0.78 | TRPV1 (0.46) | EPHX2TDP1TRPV1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |