Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936439 | 0.85 | KMT2A (0.57) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL1972890 | 0.79 | KMT2A (0.65) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL27300181 | 0.77 | KMT2A (0.63) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL29406731 | 0.76 | PRSS1 (0.50) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL229507 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL9344000 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL6114729 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL14422308 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL7999646 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 | |
| SCHEMBL4594148 | 0.76 | KMT2A (0.61) | KMT2ACA2CA1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106800-A1 | Furans | CIBA-GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |