Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099902 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11102337 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11103431 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11081172 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11074936 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11102844 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11109728 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Miloxacin SCHEMBL152466 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL24445 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Miloxacin SCHEMBL29386043 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1CYP1A2CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439436-A | BACTERICIDES | STERLING DRUG INC. (US) | 1984-03-27 | — | — | US | claimed |
| EP-0101951-A1 | 1,3-Dioxolo(4,5-g)quinolines and preparation thereof | STERLING DRUG INC. (US) | 1984-03-07 | — | — | EP | claimed |
| US-4439436-A | BACTERICIDES | STERLING DRUG INC. (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0101951-A1 | 1,3-Dioxolo(4,5-g)quinolines and preparation thereof | STERLING DRUG INC. (US) | 1984-03-07 | — | — | EP | disclosed |