Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28078750 | 0.83 | TSHR (0.83) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL9183136 | 0.83 | TSHR (1.00) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Benzene SCHEMBL9464161 | 0.83 | TSHR (1.00) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Hydrogen Peroxide SCHEMBL29071816 | 0.83 | TSHR (1.00) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL22820 | 0.83 | TSHR (1.00) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Methyl Alcohol SCHEMBL28396775 | 0.82 | TDP1 (0.96) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL11143628 | 0.82 | TDP1 (0.96) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL28771784 | 0.82 | TDP1 (0.96) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Bicarbonate SCHEMBL28102775 | 0.82 | TDP1 (0.96) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Methane SCHEMBL27867863 | 0.82 | TDP1 (0.96) | TSHRTDP1ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373821-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (HK) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024056019-A1 | BICYCLIC COMPOUNDS AS CDK INHIBITORS | BEIGENE, LTD. (KY) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023134712-A1 | ANTIDIABETIC COMPOUNDS AND COMPOSITIONS | REZUBIO PHARMACEUTICALS CO., LTD (CN) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023001237-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (CN) | 2023-01-26 | — | — | WO | disclosed |
| CN-115073342-A | Method and device for continuously preparing powdered benzoyl peroxide | 睦化(上海)流体工程有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115023426-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |
| WO-2022148422-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2022-07-14 | — | — | WO | disclosed |
| WO-2020004521-A1 | THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2020-01-02 | — | — | WO | disclosed |
| WO-2019034009-A1 | Btk INHIBITORS WITH IMPROVED DUAL SELECTIVITY | BEIGENE, LTD. (KY) | 2019-02-21 | — | — | WO | disclosed |
| EP-3114190-A1 | BI-NUCLEAR MAIN GROUP METAL PHOSPHORESCENT EMITTER | Siemens Aktiengesellschaft (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2016161572-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2016-10-13 | — | — | WO | disclosed |
| WO-2015180901-A1 | BI-NUCLEAR MAIN GROUP METAL PHOSPHORESCENT EMITTER | SIEMENS AKTIENGESELLSCHAFT (DE) | 2015-12-03 | — | — | WO | disclosed |
| CN-101903375-B | Carboxyl- or hydroxyl-substituted benzimidazole derivatives | HOFFMANN LA ROCHE | 2014-05-21 | — | — | CN | disclosed |
| CN-102083816-A | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE SA | 2011-06-01 | — | — | CN | disclosed |
| CN-101903375-A | Carboxyl- or hydroxyl-substituted benzimidazole derivatives | HOFFMANN LA ROCHE | 2010-12-01 | — | — | CN | disclosed |
| US-4431590-A | 1-Chlorosulphonyl-2,3,4,10-tetrahydro-1H-chromeno[3,4-c]azet-2-one | HOFFMANN-LA ROCHE INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4322360-A | Process for producing imidazolidone intermediates of biotin | HOFFMANN-LA ROCHE INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4284788-A | Imidazolidone intermediates of biotin | HOFFMANN-LA ROCHE INC. (US) | 1981-08-18 | — | — | US | disclosed |