Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971318 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL15865383 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL2333322 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL8419487 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL13716189 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL29132046 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL12660048 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL1641404 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B | |
| SCHEMBL12425238 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL13189973 | 0.74 | PDE4B (0.52) | SMN1; SMN2CYP2C19NPC1RAB9APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |