Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.69 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11263678 | 0.98 | CYP4F2 (0.67) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL4270902 | 0.90 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL27567553 | 0.89 | CYP4F2 (0.71) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL9713399 | 0.88 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL11404769 | 0.88 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL69660 | 0.88 | CYP4F2 (0.86) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL5201213 | 0.87 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1HSD17B10LMNA | |
| SCHEMBL1067476 | 0.87 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL11214621 | 0.86 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL11867095 | 0.86 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224258-B1 | 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS | GENENTECH INC (US) | 2019-08-14 | — | — | EP | disclosed |
| CN-1168727-C | Substituted benzimidazole | ���ĵ�˹ҩ��¹�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1356995-A | Substituted benzimidazole | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | CN | disclosed |
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |