Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972699 | 0.93 | CNR1 (0.67) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL11080762 | 0.92 | CNR1 (0.67) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL10976108 | 0.90 | CNR1 (0.65) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL11071848 | 0.87 | CNR1 (0.57) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL10974453 | 0.85 | CNR1 (0.69) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL10977617 | 0.83 | CNR1 (0.46) | CNR1CNR2KMT2AMAPTALDH1A1 | |
| SCHEMBL10974218 | 0.83 | CNR1 (0.66) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL10982516 | 0.82 | CNR1 (0.59) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL11282547 | 0.82 | CNR1 (0.49) | CNR1CNR2KMT2AKDM4EMAPT | |
| SCHEMBL11073496 | 0.81 | CNR1 (0.68) | CNR1CNR2KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | claimed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | claimed |