Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21119006 | 0.85 | TP53 (0.64) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL21119007 | 0.85 | TP53 (0.64) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL11086325 | 0.81 | TP53 (0.45) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL11087869 | 0.80 | TP53 (0.48) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL11079414 | 0.80 | TP53 (0.48) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL1715182 | 0.79 | TP53 (0.44) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL5802494 | 0.79 | TP53 (0.44) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL961994 | 0.79 | TP53 (0.52) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL6454276 | 0.79 | TP53 (0.56) | TP53HBBSMN1; SMN2DHFRPOLB | |
| SCHEMBL14453335 | 0.78 | TP53 (0.47) | TP53HBBSMN1; SMN2DHFRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459392-A | Method of making and polymer of heat resistant polyester using diglycidilhydantoins, diglycidiluracils, diglycidilbarbituric and isocyanuric acids | UNITIKA LIMITED (JP) | 1984-07-10 | — | — | US | disclosed |