Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076256 | 1.00 | TDP1 (0.50) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079262 | 0.92 | TDP1 (0.49) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079265 | 0.92 | TDP1 (0.49) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079910 | 0.91 | TDP1 (0.61) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079907 | 0.91 | TDP1 (0.61) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11074214 | 0.90 | TDP1 (0.47) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11074217 | 0.90 | TDP1 (0.47) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079086 | 0.89 | TDP1 (0.47) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11079085 | 0.89 | TDP1 (0.47) | TDP1ALDH1A1RAB9ATRPV1EPHX2 | |
| SCHEMBL11077282 | 0.88 | TRPV1 (0.46) | TDP1ALDH1A1RAB9ATRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |