Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441474 | 0.93 | MEN1 (0.42) | MEN1KMT2ATDP1 | |
| SCHEMBL8681403 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL4371710 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL6302344 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL9392822 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL25368990 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL16537519 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL679404 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL7904420 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL3364354 | 0.89 | MEN1 (0.50) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486355-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-04 | — | — | US | disclosed |
| US-4385070-A | CYCLOPROPANE DERIVATIVES AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| EP-0016513-B1 | ESTERS OF HALOGENATED SUBSTITUTED CYCLOPROPANOIC ACIDS, THEIR PREPARATION AND USE AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-23 | — | — | EP | disclosed |