Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.68 |
| ▸ | CNR1 | P21554 | 8/20 | 0.67 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.67 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.67 |
| ▸ | FAAH | O00519 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | LDHA | P00338 | 1/20 | 0.67 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.67 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.67 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076813 | 1.00 | CNR2 (0.68) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL24518125 | 0.91 | CNR2 (0.73) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL25791579 | 0.90 | CNR2 (0.66) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL25243340 | 0.89 | CNR2 (0.65) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL11937356 | 0.89 | CNR2 (0.67) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545263 | 0.88 | CNR2 (0.71) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL19129031 | 0.87 | CNR2 (0.73) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545433 | 0.87 | CNR2 (0.73) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545449 | 0.87 | CNR2 (0.70) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545323 | 0.86 | CNR2 (0.69) | CNR2CNR1ABHD12ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438207-A | RADIOACTIVE IODINE LABELED | HOFFMANN-LA ROCHE INC. (US) | 1984-03-20 | — | — | US | claimed |
| US-4438207-A | RADIOACTIVE IODINE LABELED | HOFFMANN-LA ROCHE INC. (US) | 1984-03-20 | — | — | US | disclosed |
| EP-0027567-B1 | TETRAHYDROCANNABINOL DERIVATIVES, 125I-LABELED TETRAHYDROCANNABINOL DERIVATIVES, IMMUNOGENS YIELDING ANTIBODIES AND RADIOIMMUNOASSAY FOR DETECTING CANNABINOIDS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-05-04 | — | — | EP | disclosed |
| EP-0027567-A1 | Tetrahydrocannabinol derivatives, 125I-labeled tetrahydrocannabinol derivatives, immunogens yielding antibodies and radioimmunoassay for detecting cannabinoids | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-29 | — | — | EP | disclosed |