SCHEMBL11076841

SCHEMBL11076841

CCOC(=O)C=Cc1ccc(C=Cc2ccc(C=CC(=O)O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.73
CA7 P43166 3/20 0.73
CA9 Q16790 3/20 0.73
CA14 Q9ULX7 3/20 0.73
CA1 P00915 2/20 0.73
CA2 P00918 2/20 0.73
CYP3A4 P08684 1/20 0.68
DPP4 P27487 2/20 0.62
TTR P02766 1/20 0.62
HCAR2 Q8TDS4 3/20 0.58
MAOB P27338 1/20 0.56
THRB P10828 1/20 0.54
ATM Q13315 1/20 0.54
FDPS P14324 1/20 0.54
PTGS2 P35354 1/20 0.53
AKR1B10 O60218 2/20 0.52
AKR1B1 P15121 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11076826 1.00 CA12 (0.73) CA12CA7CA9CA14CA1
SCHEMBL1579390 0.98 CA12 (0.75) CA12CA7CA9CA14CA1
SCHEMBL1579391 0.98 CA12 (0.75) CA12CA7CA9CA14CA1
SCHEMBL27792934 0.98 CA12 (0.75) CA12CA7CA9CA14CA1
SCHEMBL1260527 0.93 CA12 (0.83) CA12CA7CA9CA14CA1
SCHEMBL3143890 0.93 CA12 (0.83) CA12CA7CA9CA14CA1
Ethyl Cinnamate SCHEMBL29527453 0.92 CA12 (0.66) CA12CA7CA9CA14CA1
SCHEMBL13957401 0.91 CA12 (0.86) CA12CA7CA9CA14CA1
SCHEMBL10939791 0.91 CA12 (0.86) CA12CA7CA9CA14CA1
SCHEMBL5059085 0.91 CA12 (0.86) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4440694-A FROM STILBENE DIACYL HALIDES, PALLADIUM CATALYST CIBA-GEIGY CORPORATION (US) 1984-04-03 US disclosed