SCHEMBL11077026

SCHEMBL11077026

CCCC(C#N)(CCC)C(O)C(Cc1ccc(F)cc1)n1ccnc1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 17/20 0.46
CYP17A1 P05093 2/20 0.40
CYP24A1 Q07973 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11072400 0.82 MEN1 (0.52) CYP19A1
SCHEMBL11078658 0.77 CYP24A1 (0.51) CYP19A1CYP17A1CYP24A1
SCHEMBL11079140 0.73 MEN1 (0.51) CYP19A1CYP24A1
SCHEMBL11095315 0.72 MEN1 (0.54) CYP19A1
SCHEMBL11068105 0.67 CYP24A1 (0.61) CYP19A1CYP17A1CYP24A1
SCHEMBL8408716 0.67 CYP19A1 (0.62) CYP19A1CYP17A1
SCHEMBL11081016 0.65 KMT2A (0.59) CYP19A1
SCHEMBL9996089 0.65 MEN1 (0.49) CYP19A1
SCHEMBL29571712 0.64 CYP19A1 (1.00) CYP19A1CYP17A1
Hydrochloric Acid SCHEMBL412437 0.64 MEN1 (0.48) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125409-A2 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them SCHERING AKTIENGESELLSCHAFT (DE) 1984-11-21 EP disclosed