SCHEMBL1107766

SCHEMBL1107766

CC(C)(Sc1ccccc1)Sc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MGLL Q99685 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ALOX15 P16050 2/20 0.41
HPN P05981 1/20 0.41
SIRT5 Q9NXA8 1/20 0.41
ALDH1A1 P00352 5/20 0.39
MAPK1 P28482 3/20 0.39
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575613 0.82 HSD17B10 (0.45) MAPTHPGDSMN1; SMN2MGLLHSD17B10
Fluoride SCHEMBL777953 0.80 HSD17B10 (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10
Fluoride SCHEMBL1335636 0.80 HSD17B10 (0.43) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1111636 0.78 HPGD (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL21011381 0.78 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL19622359 0.78 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL7529152 0.78 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL13299807 0.76 MAPK1 (0.42) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL11640269 0.75 HPGD (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL11639651 0.75 HPGD (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008545-A1 HEAT-TREATMENT OIL COMPOSITION 出光興産株式会社 2023-02-02 WO disclosed
US-8216698-B2 Organic electroluminescence device, novel platinum complex compound and novel compound capable of being a ligand thereof FUJIFILM CORPORATION (JP) 2012-07-10 US disclosed
US-8153278-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF FUJIFILM CORPORATION (JP) 2009-10-22 US disclosed
EP-1409562-B1 HIGH REFRACTIVE INDEX OPTICAL RESIN COMPOSITION PPG IND OHIO INC (US) 2006-04-12 EP disclosed
US-6342571-B1 POLYMERIZABLE MIXTURE OF THIO(METH)ACRYLATE, VINYL AROMATIC, POLYTHIOL, AND UNSATURATED ANHYDRIDE COMONOMERS PPG INDUSTRIES OHIO, INC. 2002-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF L1CAM, PDCD1LG2, CD274 MAPT 2945/4885HPGD 3097/4885SMN1; SMN2 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.