SCHEMBL1107775

SCHEMBL1107775

CC1(C)CCN(c2ccccc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 2/20 0.53
CHRNA7 P36544 3/20 0.52
CYP3A4 P08684 3/20 0.52
MAPK1 P28482 2/20 0.52
ALOX15 P16050 1/20 0.52
CHRNB2 P17787 1/20 0.52
NFKB1 P19838 1/20 0.52
CHRNA3 P32297 1/20 0.52
CHRNA4 P43681 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
SIGMAR1 Q99720 2/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 1/20 0.50
APOBEC3A P31941 1/20 0.50
PMP22 Q01453 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28324490 0.98 USP2 (0.53) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL22857712 0.87 CYP3A4 (0.50) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL22657654 0.83 USP2 (0.52) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL28471992 0.83 USP2 (0.54) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL26834764 0.83 USP2 (0.52) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL9975647 0.79 CHRNA7 (0.53) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL1709269 0.79 USP2 (0.74) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL25367082 0.78 AKR1C3 (0.42) USP2CYP2D6CYP2C9KMT2AADRB1
SCHEMBL2975291 0.78 CYP2C19 (0.36) USP2CYP2D6CYP2C9CHRNA7CYP3A4
SCHEMBL23875490 0.78 CHKA (0.59) CYP2D6CYP2C9CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022180-B1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2022-02-23 EP disclosed
EP-3564232-A1 BMP-SIGNAL-INHIBITING COMPOUND Riken (JP) 2019-11-06 EP disclosed
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2018-06-07 US disclosed
US-9920009-B2 UV absorbing compounds, compositions comprising same and uses thereof CORAL SUNSCREEN PTY LTD (AU) 2018-03-20 US disclosed
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2016-08-25 US disclosed
CN-105793239-A UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF 珊瑚防晒私人有限公司 2016-07-20 CN disclosed
EP-3022180-A1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF Coral Sunscreen Pty Ltd (AU) 2016-05-25 EP disclosed
WO-2015006803-A1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2015-01-22 WO disclosed
US-8558221-B2 Polymeric compound containing dopant and host repeating units and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2013-10-15 US disclosed
US-8558221-B2 Polymeric compound containing dopant and host repeating units and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2013-10-15 US disclosed
US-20100289014-A1 POLYMERIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-11-18 US disclosed
US-20100289014-A1 POLYMERIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-11-18 US disclosed
US-20100264814-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-21 US disclosed
US-20100264814-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-21 US disclosed
EP-2223949-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-09-01 EP disclosed
EP-2213693-A1 POLYMERIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-08-04 EP disclosed
CN-101627042-A Substituted piperidines containing a heteroarylamide or heteroarylphenyl moiety ASTEX THERAPEUTICS LTD 2010-01-13 CN disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF FUJIFILM CORPORATION (JP) 2009-10-22 US disclosed
WO-2009023558-A1 COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS VM DISCOVERY INC. (US) 2009-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof ERCC1, ERCC4, ERCC5 USP2 954/4885CYP2D6 3450/4885CYP2C9 1147/4885
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof ERCC4, ERCC1, ERCC5 USP2 367/4885CYP2D6 3657/4885CYP2C9 937/4885
US-20090261721-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF L1CAM, PDCD1LG2, CD274 USP2 4425/4885CYP2D6 2620/4885CYP2C9 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.