Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078039 | 1.00 | GPBAR1 (0.40) | GPBAR1POLBTDP1CYP11B1CYP11B2 | |
| SCHEMBL11079529 | 0.90 | POLQ (0.36) | GPBAR1POLBTDP1LMNAMEN1 | |
| SCHEMBL11079534 | 0.90 | POLQ (0.36) | GPBAR1POLBTDP1LMNAMEN1 | |
| SCHEMBL11079064 | 0.89 | GPBAR1 (0.40) | GPBAR1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL11079068 | 0.89 | GPBAR1 (0.40) | GPBAR1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL11080525 | 0.89 | TDP1 (0.40) | GPBAR1POLBTDP1CYP11B1CYP11B2 | |
| SCHEMBL11080519 | 0.89 | TDP1 (0.40) | GPBAR1POLBTDP1CYP11B1CYP11B2 | |
| SCHEMBL11072598 | 0.87 | GPBAR1 (0.38) | GPBAR1POLBTDP1CYP11B1CYP11B2 | |
| SCHEMBL11072600 | 0.87 | GPBAR1 (0.38) | GPBAR1POLBTDP1CYP11B1CYP11B2 | |
| SCHEMBL11075800 | 0.84 | TDP1 (0.46) | POLBTDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |