Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | FDPS | P14324 | 9/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072973 | 1.00 | TSHR (0.33) | TSHRTHRBEBPSIGMAR1GGPS1 | |
| Propane SCHEMBL11126254 | 0.96 | TSHR (0.31) | TSHREBPSIGMAR1 | |
| SCHEMBL11069615 | 0.91 | TSHR (0.33) | TSHR | |
| SCHEMBL2819842 | 0.82 | — | — | |
| SCHEMBL28844645 | 0.79 | TSHR (0.52) | TSHR | |
| SCHEMBL11822285 | 0.73 | TSHR (0.36) | TSHRTHRBEBPSIGMAR1GGPS1 | |
| SCHEMBL7023862 | 0.72 | — | — | |
| SCHEMBL23700067 | 0.70 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL23700088 | 0.70 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16672477 | 0.70 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442122-A | BACTERICIDES, FUNGICIDES, ALGICIDES | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | claimed |
| US-4442122-A | BACTERICIDES, FUNGICIDES, ALGICIDES | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |