SCHEMBL11079361

SCHEMBL11079361

C1CN2CCC12.CC(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
OGFRL1 Q5TC84 1/20 0.36
CHRM1 P11229 1/20 0.36
L3MBTL3 Q96JM7 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TP53 P04637 1/20 0.35
MBTD1 Q05BQ5 1/20 0.34
TP53BP1 Q12888 1/20 0.34
L3MBTL4 Q8NA19 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9219154 0.81 KDM4E (0.46) KDM4EPOLBALDH1A1CHRM1L3MBTL3
Propionic Acid SCHEMBL9223501 0.75 KDM4E (0.50) KDM4EPOLBALDH1A1CHRM1L3MBTL3
Methyl Alcohol SCHEMBL10751983 0.74
SCHEMBL27977582 0.74 TP53 (0.38) ALDH1A1CYP2C19SMN1; SMN2TP53
Propionic Acid SCHEMBL11080011 0.73 KDM4E (0.49) KDM4EPOLBALDH1A1CHRM1L3MBTL3
SCHEMBL25107536 0.73 MEN1 (0.46) KDM4EALDH1A1CYP2C9CYP2C19CHRM1
SCHEMBL9181343 0.73 TP53 (0.42) ALDH1A1SMN1; SMN2TP53
SCHEMBL28068714 0.73 TP53 (0.42) ALDH1A1SMN1; SMN2TP53
Isobutanol SCHEMBL5921907 0.72 TSHR (0.47) KDM4EPOLBCYP2C9CYP2C19SIGMAR1
SCHEMBL4640114 0.71 TP53 (0.61) KDM4EALDH1A1CYP2C19TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447434-A ANTIULCER, ANTISECRETORY, OR ANTICHOLINERGIC AGENTS DR. KARL THOMAE GMBH (DE) 1984-05-08 US disclosed