SCHEMBL11079807

SCHEMBL11079807

CC(C)(C#N)C(O)C(Cc1ccc(Cl)cc1Cl)n1ccnc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
CYP19A1 P11511 6/20 0.47
ADRA2C P18825 2/20 0.40
CYP3A4 P08684 6/20 0.38
CYP2C9 P11712 4/20 0.38
CYP2D6 P10635 4/20 0.38
ADORA3 P0DMS8 3/20 0.38
CHRM1 P11229 3/20 0.38
SLC6A2 P23975 3/20 0.38
SLC6A4 P31645 3/20 0.38
SLC6A3 Q01959 3/20 0.38
PGR P06401 2/20 0.38
CHRM2 P08172 2/20 0.38
ADRA2A P08913 2/20 0.38
ADRB3 P13945 2/20 0.38
IDO1 P14902 2/20 0.38
ADRA2B P18089 2/20 0.38
CHRM3 P20309 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079140 0.84 MEN1 (0.51) MEN1KMT2ACYP19A1CYP3A4ADORA3
SCHEMBL3984360 0.77 CYP19A1 (0.58) MEN1KMT2ATDP1CYP19A1ADRA2C
SCHEMBL11239483 0.73 CYP19A1 (0.51) MEN1KMT2ATDP1CYP19A1ADRA2C
Hydrochloric Acid SCHEMBL11176357 0.72 CYP19A1 (0.58) MEN1KMT2ATDP1CYP19A1ADRA2C
SCHEMBL28226515 0.72 CYP19A1 (0.50) MEN1KMT2ATDP1CYP19A1ADRA2C
SCHEMBL29934164 0.70 MEN1 (1.00) MEN1KMT2ATDP1CYP19A1CYP3A4
SCHEMBL21654 0.70 MEN1 (1.00) MEN1KMT2ATDP1CYP19A1CYP3A4
SCHEMBL11489337 0.70 MEN1 (1.00) MEN1KMT2ATDP1CYP19A1CYP3A4
SCHEMBL11270467 0.70 CYP19A1 (0.47) MEN1KMT2ATDP1CYP19A1CYP3A4
SCHEMBL10973298 0.69 CYP19A1 (0.58) MEN1KMT2ATDP1CYP19A1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125409-A2 4-Azolyl-pentanenitriles, process for their preparation and biocides containing them SCHERING AKTIENGESELLSCHAFT (DE) 1984-11-21 EP disclosed