SCHEMBL1108031

SCHEMBL1108031

CCC(C)C(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
USP2 O75604 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
RECQL P46063 1/20 0.36
GAA P10253 1/20 0.35
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108023 1.00 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL18412471 0.98 TSHR (0.42) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL1108017 0.94 TSHR (0.37) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL14191163 0.88 HTT (0.38) HTT
SCHEMBL13930912 0.88 USP2 (0.40) TSHRUSP2MAPTCYP1A2CYP2C19
SCHEMBL16683610 0.87 HTT (0.34) TSHRUSP2MAPTGAAHTT
SCHEMBL17853393 0.85 HTT (0.33) MAPTKDM4EHTT
SCHEMBL14094642 0.85 HTT (0.33) MAPTKDM4EHTT
SCHEMBL1108085 0.85 HTT (0.33) MAPTKDM4EHTT
SCHEMBL1108107 0.85 USP2 (0.38) TSHRUSP2MAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999436-B2 Optical functional film, antireflection film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2015-04-07 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20120003467-A1 Antistatic laminate, optical film, polarizing plate, image display device and production method of antistatic laminate FUJI FILM CORPORATION (JP) 2012-01-05 US disclosed
US-8039065-B2 Antireflection film, polarizing plate, method for producing them, liquid crystal display element, liquid crystal display device, and image display device FUJIFILM CORPORATION (JP) 2011-10-18 US disclosed
US-8039098-B2 Coating composition, optical film, antireflective film, polarizing plate, and display device using the same FUJIFILM CORPORATION (JP) 2011-10-18 US disclosed
US-20110242654-A1 Hardcoat layer-forming composition, optical film, production method of optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
US-7872716-B2 Optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7622194-B2 use of a transparent support having specific physical properties during the spreading of a functional layer makes it possible to control the spread and the penetration of solvent and hence provide a good quality optical film having little coating defects, reducing impact of residual solvent; LCDs FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-7502088-B2 Liquid crystal display device having an antiglare layer FUJIFILM CORPORATION (JP) 2009-03-10 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080038561-A1 Coating Composition, Optical Film, Antireflective, Film, Polarizing Plate, And Display Device Using The Same FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-7307679-B2 Liquid-crystal display and polarizing plate FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-20070146887-A1 Antireflection film, polarizing plate, method for producing them, liquid cryatal display element, liquid crystal display device, and image display device FUJI PHOTO FILM CO., LTD. (JP) 2007-06-28 US disclosed
US-20070035839-A1 Optical functional film, antireflection film, polarizing plate and image display device FUJI PHOTO FILM CO., LTD. (JP) 2007-02-15 US disclosed
US-20070002232-A1 Optical compensation film, polarizing plate and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 US disclosed