Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083382 | 0.95 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11092766 | 0.91 | MAPT (0.49) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11090491 | 0.89 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11089457 | 0.86 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11083726 | 0.85 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11083094 | 0.82 | PDE3B (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11087323 | 0.82 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11086289 | 0.81 | PDE3B (0.51) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11083063 | 0.81 | HRH3 (0.43) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11094108 | 0.81 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |