⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6728521 | 0.73 | — | — | |
| SCHEMBL828954 | 0.72 | — | — | |
| SCHEMBL3893707 | 0.72 | — | — | |
| SCHEMBL5429936 | 0.72 | — | — | |
| SCHEMBL3892557 | 0.72 | — | — | |
| SCHEMBL478004 | 0.70 | — | — | |
| SCHEMBL477938 | 0.70 | — | — | |
| SCHEMBL42446 | 0.70 | — | — | |
| SCHEMBL27480254 | 0.69 | — | — | |
| SCHEMBL229948 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124342-A2 | Process for preparing isoxazolyl imidazolidinones | ELI LILLY AND COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4471123-A | Synthesis of isoxazolyl imidazolidinones | ELI LILLY AND COMPANY (US) | 1984-09-11 | — | — | US | disclosed |