Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.67 |
| ▸ | LCK | P06239 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.66 |
| ▸ | FLT1 | P17948 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.58 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086239 | 0.99 | EGFR (0.68) | EGFRLCKHTTMAPTGRM1 | |
| SCHEMBL11090480 | 0.87 | KDM4E (0.66) | EGFRLCKKDRFLT1TTBK1 | |
| SCHEMBL11093822 | 0.87 | TTBK1 (0.60) | EGFRLCKHTTMAPTGRM1 | |
| Hydrochloric Acid SCHEMBL11084310 | 0.86 | TTBK1 (0.58) | EGFRLCKHTTMAPTGRM1 | |
| Hydrochloric Acid SCHEMBL11087390 | 0.86 | KDM4E (0.64) | EGFRLCKKDRFLT1NPC1 | |
| SCHEMBL11091766 | 0.85 | MAPK1 (0.62) | EGFRLCKHTTMAPTKDR | |
| Hydrochloric Acid SCHEMBL11087905 | 0.83 | MAPK1 (0.65) | EGFRLCKHTTMAPTKDR | |
| SCHEMBL29236930 | 0.82 | ABCG2 (0.64) | EGFRLCKMAPTKDRFLT1 | |
| SCHEMBL11084344 | 0.81 | EGFR (0.70) | EGFRLCKHTTKDRMAPK1 | |
| SCHEMBL8205589 | 0.81 | EGFR (0.73) | EGFRKDRRAF1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464375-A | ANALGESIC, ANTIINFLAMMATORY | SANKYO CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4322420-A | Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |