Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136064 | 0.92 | SLC6A4 (0.52) | HSD17B10TDP1LMNAL3MBTL1NR1I2 | |
| SCHEMBL6051485 | 0.89 | NR1I2 (0.62) | HSD17B10TDP1NR1I2PGRPPARG | |
| SCHEMBL9076452 | 0.89 | NR1I2 (0.62) | HSD17B10TDP1NR1I2PGRPPARG | |
| SCHEMBL6051490 | 0.89 | NR1I2 (0.62) | HSD17B10TDP1NR1I2PGRPPARG | |
| SCHEMBL9076453 | 0.89 | NR1I2 (0.62) | HSD17B10TDP1NR1I2PGRPPARG | |
| SCHEMBL11842307 | 0.89 | NR1I2 (0.62) | HSD17B10TDP1NR1I2PGRPPARG | |
| SCHEMBL11135000 | 0.89 | NR1I2 (0.51) | HSD17B10TDP1LMNAL3MBTL1NR1I2 | |
| SCHEMBL11225158 | 0.88 | SLC6A4 (0.50) | HSD17B10TDP1LMNAL3MBTL1NR1I2 | |
| SCHEMBL11225159 | 0.88 | SLC6A4 (0.50) | HSD17B10TDP1LMNAL3MBTL1NR1I2 | |
| SCHEMBL9375027 | 0.88 | SLC6A4 (0.51) | HSD17B10TDP1LMNANR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |