SCHEMBL11084256

SCHEMBL11084256

CC(Oc1cccc(Oc2ccc(Cl)cc2)c1[N+](=O)[O-])C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.45
TSHR P16473 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
PPARA Q07869 4/20 0.44
KMT2A Q03164 1/20 0.43
TLR8 Q9NR97 1/20 0.41
PPARG P37231 5/20 0.40
CYP1A2 P05177 1/20 0.40
GAA P10253 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PTGDR2 Q9Y5Y4 2/20 0.39
PTGDR Q13258 1/20 0.39
LMNA P02545 1/20 0.39
SLC6A4 P31645 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11093485 0.89 KMT2A (0.43) PPARAKMT2ATLR8PPARGCYP1A2
SCHEMBL11091006 0.88 KMT2A (0.43) PPARAKMT2ATLR8PPARGCYP1A2
SCHEMBL11087937 0.88 KMT2A (0.43) PPARAKMT2ATLR8PPARGCYP1A2
SCHEMBL11079040 0.85 PTGDR2 (0.43) PPARAKMT2APPARGCYP1A2GAA
SCHEMBL11082101 0.85 TSHR (0.51) HTR2ATSHRHTR2CHTR2BPPARA
SCHEMBL11092193 0.84 TSHR (0.50) HTR2ATSHRHTR2CHTR2BKMT2A
SCHEMBL11839319 0.82 KMT2A (0.59) HTR2ATSHRHTR2CHTR2BPPARA
Hydrochloric Acid SCHEMBL11841321 0.80 KMT2A (0.58) HTR2ATSHRHTR2CHTR2BPPARA
SCHEMBL3489565 0.79 KMT2A (0.49) HTR2ATSHRHTR2CHTR2BPPARA
SCHEMBL11198233 0.78 TSHR (0.48) HTR2ATSHRHTR2CHTR2BPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478634-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1984-10-23 US disclosed
US-4402729-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1983-09-06 US disclosed