Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 7/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084874 | 1.00 | KCNH2 (0.45) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL10859980 | 0.91 | NR1I2 (0.46) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL10859989 | 0.91 | NR1I2 (0.46) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL10856147 | 0.87 | TDP1 (0.55) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL10856153 | 0.87 | TDP1 (0.55) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL11115828 | 0.86 | NR1I2 (0.47) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL11115825 | 0.86 | NR1I2 (0.47) | KCNH2NR1I2HTR2CTDP1APAF1 | |
| SCHEMBL10782218 | 0.86 | MAPT (0.61) | NR1I2HTR2CTDP1TSHRLMNA | |
| SCHEMBL10781239 | 0.84 | NR1I2 (0.54) | KCNH2NR1I2HTR2CTDP1TSHR | |
| SCHEMBL10849600 | 0.84 | NR1I2 (0.57) | KCNH2NR1I2HTR2CTDP1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468515-A | CEPRALOSPORINS, MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4331665-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |