Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471768 | 0.86 | MAPT (0.59) | EPHX2KMT2AMEN1GAAPOLB | |
| SCHEMBL1601239 | 0.83 | SMN1; SMN2 (0.55) | GAAPOLBMAPTHTTRAB9A | |
| SCHEMBL18025700 | 0.83 | GAA (0.50) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL10419324 | 0.80 | GAA (0.68) | EPHX2KMT2AMEN1GAAPOLB | |
| SCHEMBL27350327 | 0.80 | MEN1 (0.65) | EPHX2KMT2AMEN1POLBMAPT | |
| SCHEMBL2228878 | 0.79 | MEN1 (0.54) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL19991711 | 0.78 | MAPT (0.56) | KMT2AMEN1GAAMAPTNPSR1 | |
| SCHEMBL24969427 | 0.78 | MAPT (0.69) | EPHX2KMT2AMEN1GAAPOLB | |
| SCHEMBL3102077 | 0.77 | KCNQ2 (0.63) | EPHX2KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL17161320 | 0.77 | MEN1 (0.73) | EPHX2KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481356-A | MEDICAL DIAGNOSIS | THE UPJOHN COMPANY (US) | 1984-11-06 | — | — | US | disclosed |
| US-4366320-A | 4-Substituted phenyl-1,2,4-triazoline-3,5-diones and their dihydro analogs as analytical reagents | THE UPJOHN COMPANY (US) | 1982-12-28 | — | — | US | disclosed |