Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084352 | 0.92 | S1PR4 (0.36) | INPP5ALPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL11084350 | 0.92 | S1PR4 (0.36) | INPP5ALPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL11090279 | 0.92 | S1PR4 (0.36) | INPP5ALPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL11090273 | 0.92 | S1PR4 (0.36) | INPP5ALPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL11289177 | 0.92 | S1PR4 (0.36) | INPP5ALPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL496837 | 0.81 | AKT1 (0.41) | — | |
| Phosphoric Acid SCHEMBL11085351 | 0.78 | S1PR1 (0.36) | LPAR3LPAR1LPAR2S1PR4S1PR1 | |
| SCHEMBL497094 | 0.77 | S1PR4 (0.33) | S1PR4S1PR1S1PR3S1PR5S1PR2 | |
| SCHEMBL496839 | 0.74 | AKT1 (0.39) | — | |
| SCHEMBL11126408 | 0.74 | AKT1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |