Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PPOX | P50336 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085628 | 0.94 | TDP1 (0.49) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11081610 | 0.91 | TDP1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11083123 | 0.91 | TDP1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11089314 | 0.89 | TDP1 (0.47) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11090667 | 0.86 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11087944 | 0.84 | TDP1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11084866 | 0.82 | TDP1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11084325 | 0.81 | MEN1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11087930 | 0.81 | TDP1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10614668 | 0.80 | MEN1 (0.61) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402729-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-06 | — | — | US | claimed |
| US-4478634-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4402729-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |