Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086318 | 1.00 | MEN1 (0.73) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11085731 | 0.94 | MEN1 (0.64) | MEN1KMT2APOLB | |
| SCHEMBL11085732 | 0.94 | MEN1 (0.64) | MEN1KMT2APOLB | |
| SCHEMBL11086567 | 0.92 | MEN1 (0.64) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11086573 | 0.92 | MEN1 (0.64) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11089833 | 0.89 | MEN1 (0.61) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11089836 | 0.89 | MEN1 (0.61) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11079429 | 0.89 | MEN1 (0.63) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11079427 | 0.89 | MEN1 (0.63) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL10857514 | 0.89 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428952-A | Substituted pyrrolo[2,1-b]quinazolines and pyrido[2,1-b]quinazolines useful for the treatment of or the prevention of gastrointestinal ulcers | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-01-31 | — | — | US | disclosed |