Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | HRH2 | P25021 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837381 | 0.94 | KDM4E (0.74) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10838747 | 0.93 | KDM4E (0.69) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10838350 | 0.90 | KDM4E (0.74) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11229224 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10838753 | 0.89 | KDM4E (0.70) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11107907 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11094138 | 0.89 | KDM4E (0.64) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL10837355 | 0.88 | KDM4E (0.69) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11103851 | 0.88 | KDM4E (0.66) | KDM4EALDH1A1HRH2HRH3 | |
| SCHEMBL11103614 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433154-A | ANTIHISTAMINES, ANTIULCER AGENTS | SHIONOGI & COMPANY, LIMITED (JP) | 1984-02-21 | — | — | US | claimed |
| US-4433154-A | ANTIHISTAMINES, ANTIULCER AGENTS | SHIONOGI & COMPANY, LIMITED (JP) | 1984-02-21 | — | — | US | disclosed |