Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087774 | 1.00 | KCNH2 (0.48) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11089492 | 0.92 | KCNH2 (0.49) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11089490 | 0.92 | KCNH2 (0.49) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11082764 | 0.91 | KCNH2 (0.47) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11082766 | 0.91 | KCNH2 (0.47) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11082844 | 0.91 | TDP1 (0.57) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL11082838 | 0.91 | TDP1 (0.57) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10644409 | 0.90 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10644408 | 0.90 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10643602 | 0.89 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |