Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736603 | 0.86 | KMT2A (0.49) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL727064 | 0.84 | TSHR (0.59) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL17094704 | 0.83 | HSD17B3 (0.50) | KMT2ATSHRLMNARAB9ASMN1; SMN2 | |
| SCHEMBL11637468 | 0.81 | USP5 (0.50) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL11658672 | 0.80 | GSK3B (0.53) | TSHRHIF1AALDH1A1 | |
| SCHEMBL5054876 | 0.80 | GSK3B (0.57) | — | |
| SCHEMBL2875993 | 0.79 | USP5 (0.49) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL5378544 | 0.79 | KMT2A (0.49) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL11739448 | 0.79 | KMT2A (0.58) | USP5KMT2ANR4A2PKMTSHR | |
| SCHEMBL11536711 | 0.79 | KMT2A (0.58) | USP5KMT2ANR4A2PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447604-A | ANTICANCER AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0020785-B1 | HEXAHYDRONAPHTHO(1',2':4,5)IMIDAZO(2,1-B)-THIAZOLE DERIVATIVES AND PROCESS FOR PREPARING SAME | TEIJIN LIMITED (JP) | 1982-11-24 | — | — | EP | disclosed |
| US-4347369-A | IMMUNOLOGY, ANTICARCINOGENIC, ANTIARTHRITIC, ANTHELMINTICS | TEIJIN LIMITED (JP) | 1982-08-31 | — | — | US | disclosed |
| US-4302585-A | IMMUNOSUPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-11-24 | — | — | US | disclosed |
| US-4293696-A | IMMUNOSTIMULANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| EP-0020785-A1 | HEXAHYDRONAPHTHO(1',2':4,5)IMIDAZO(2,1-b)-THIAZOLE DERIVATIVES AND PROCESS FOR PREPARING SAME | TEIJIN LIMITED (JP) | 1981-01-07 | — | — | EP | disclosed |
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |