Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965412 | 0.79 | KDM4E (0.56) | CHEK1RARBKDM4ERECQLMAPT | |
| SCHEMBL16305604 | 0.78 | APP (0.53) | CHEK1RARBKDM4ERECQLABCB1 | |
| SCHEMBL12703538 | 0.77 | KDM4E (0.61) | CHEK1RARBKDM4ERECQLMAPT | |
| SCHEMBL3611926 | 0.77 | KDM4E (0.61) | CHEK1RARBKDM4ERECQLMAPT | |
| SCHEMBL842057 | 0.76 | APP (0.57) | KDM4ERECQLMAPTAPP | |
| SCHEMBL1478767 | 0.76 | APP (0.57) | KDM4ERECQLMAPTAPP | |
| SCHEMBL16305613 | 0.76 | APP (0.57) | KDM4ERECQLMAPTAPP | |
| SCHEMBL3671202 | 0.76 | HDAC4 (0.56) | KDM4EMAPT | |
| SCHEMBL22375453 | 0.75 | KDM4E (0.46) | CHEK1RARBKDM4ERECQLABCB1 | |
| SCHEMBL13554406 | 0.73 | CYP3A4 (0.50) | CHEK1RARBKDM4ERECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153440-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110086431-A1 | Methods for Altering Surface Characteristics of Microspheres | LUMINEX CORPORATION (US) | 2011-04-14 | — | — | US | disclosed |
| US-7867774-B2 | Methods for altering surface characteristics of microspheres | LUMINEX CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |