Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238916 | 0.75 | CNR2 (0.62) | MAPTKDM4EALDH1A1CNR2CA1 | |
| Syringate SCHEMBL159392 | 0.74 | CA12 (0.67) | MAPTKDM4EALDH1A1CNR2CA1 | |
| SCHEMBL2114318 | 0.74 | KMT2A (0.61) | MAPTKDM4EALDH1A1CNR2CA1 | |
| Methyl Syringate SCHEMBL211747 | 0.74 | MEN1 (0.61) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL731344 | 0.72 | MAPT (0.53) | MAPTKDM4EALDH1A1CNR2CA1 | |
| SCHEMBL10683847 | 0.72 | KDM4E (0.53) | MAPTKDM4EALDH1A1CNR2CA1 | |
| SCHEMBL13909003 | 0.72 | MAPT (0.53) | MAPTKDM4EALDH1A1CNR2CA1 | |
| SCHEMBL3195430 | 0.72 | MAPT (0.53) | MAPTKDM4EALDH1A1CNR2CA1 | |
| SCHEMBL31395140 | 0.71 | KDM4E (0.48) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL24856262 | 0.71 | MAPT (0.51) | MAPTKDM4EALDH1A1CNR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035624-B1 | ALDEHYDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-07-04 | — | — | EP | disclosed |
| EP-0035624-A2 | Aldehydes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-09-16 | — | — | EP | disclosed |
| EP-0003212-A1 | 2.4-Diamino-5-benzylpyrimidines, pharmaceutical compositions containing them and their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-08-08 | — | — | EP | disclosed |