Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443110 | 0.79 | MAPT (0.50) | KDM4EADORA2AADORA1RXFP1MAPT | |
| SCHEMBL13458067 | 0.78 | DYRK1A (0.61) | ADORA2AADORA1DYRK1ACLK4MAPT | |
| SCHEMBL13381758 | 0.76 | MAPT (0.49) | KDM4EADORA2AADORA1DYRK1ACLK4 | |
| SCHEMBL19243796 | 0.75 | DYRK1A (0.50) | ADORA2AADORA1DYRK1ACLK4MAPT | |
| SCHEMBL19554539 | 0.74 | MAOB (0.48) | KDM4EGLASQORADORA2AADORA1 | |
| SCHEMBL2056993 | 0.74 | HPGD (0.56) | KDM4EGLASQORADORA2AADORA1 | |
| SCHEMBL24257700 | 0.73 | BTK (0.54) | KDM4EGLASQORADORA2AADORA1 | |
| SCHEMBL30453695 | 0.73 | BTK (0.54) | KDM4EGLASQORADORA2AADORA1 | |
| SCHEMBL1867048 | 0.72 | DYRK1A (0.55) | KDM4EGLASQORADORA2AADORA1 | |
| SCHEMBL15308478 | 0.72 | ATR (0.57) | KDM4EGLAADORA2AADORA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |