Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087319 | 0.88 | KMT2A (0.52) | KMT2APOLBL3MBTL1CYP1A2GAA | |
| SCHEMBL11609561 | 0.88 | KMT2A (0.57) | KMT2APOLBL3MBTL1CYP1A2GAA | |
| SCHEMBL11091355 | 0.86 | KMT2A (0.50) | KMT2APOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11084975 | 0.86 | KMT2A (0.50) | KMT2APOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11090402 | 0.86 | KMT2A (0.50) | KMT2APOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11085493 | 0.86 | KMT2A (0.50) | KMT2APOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11092136 | 0.84 | KMT2A (0.51) | KMT2APOLBL3MBTL1CYP1A2GAA | |
| SCHEMBL11092339 | 0.84 | KMT2A (0.48) | KMT2APOLBL3MBTL1CYP1A2GAA | |
| SCHEMBL11087761 | 0.84 | KMT2A (0.48) | KMT2APOLBL3MBTL1CYP1A2GAA | |
| SCHEMBL11088768 | 0.81 | KMT2A (0.54) | KMT2APOLBL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |