Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | GLA | P06280 | 1/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | EGFR | P00533 | 11/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | PRNP | P04156 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11088537 | 0.98 | KDM4E (0.81) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11086546 | 0.92 | KDM4E (0.80) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL18895185 | 0.91 | KDM4E (1.00) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11090912 | 0.91 | KDM4E (0.78) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11091582 | 0.87 | EGFR (0.68) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8870666 | 0.86 | EGFR (0.81) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4586988 | 0.86 | KDM4E (0.82) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11087397 | 0.85 | EGFR (0.66) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4586685 | 0.83 | EGFR (0.75) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4355658 | 0.82 | EGFR (1.00) | KDM4EMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464375-A | ANALGESIC, ANTIINFLAMMATORY | SANKYO CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4322420-A | Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |