Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 17/20 | 0.44 |
| ▸ | PPARG | P37231 | 16/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587966 | 0.85 | CYP1A2 (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL27259282 | 0.85 | CYP1A2 (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL11097232 | 0.83 | PPARA (0.53) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8508876 | 0.81 | MAPT (0.53) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| Potassium Ion SCHEMBL10913562 | 0.81 | MAPT (0.69) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL10414560 | 0.80 | MAPT (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL30469352 | 0.80 | MAPT (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL11114198 | 0.80 | MAPT (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9320814 | 0.79 | PPARA (0.65) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL7610992 | 0.78 | MAPT (0.56) | SMN1; SMN2TP53CYP1A2CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444584-A | Ethyl 2[4-(7-chloroquinolin-3-yloxy)phenoxy]propionate, the N-oxide, and herbicidal compositions and methods employing them | ICI AUSTRALIA LIMITED (AU) | 1984-04-24 | — | — | US | disclosed |