Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.59 |
| ▸ | CSF1R | P07333 | 6/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086154 | 0.99 | EGFR (0.58) | EGFRCSF1RPDGFRBPDGFRAABCG2 | |
| SCHEMBL23577599 | 0.80 | MAPT (0.57) | EGFRPDGFRBABCG2MAPTALDH1A1 | |
| SCHEMBL30961066 | 0.80 | MAPT (0.57) | EGFRPDGFRBABCG2MAPTALDH1A1 | |
| SCHEMBL23601302 | 0.77 | ABCG2 (0.54) | EGFRABCG2MAPT | |
| SCHEMBL3530093 | 0.77 | EGFR (0.50) | EGFRPDGFRBABCG2MAPTALDH1A1 | |
| SCHEMBL11083826 | 0.77 | CSF1R (0.79) | EGFRCSF1RPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL11094140 | 0.76 | CSF1R (0.77) | EGFRCSF1RPDGFRBPDGFRA | |
| SCHEMBL3109912 | 0.76 | EGFR (1.00) | EGFRCSF1RPDGFRBPDGFRA | |
| SCHEMBL4586983 | 0.74 | EGFR (0.55) | EGFRCSF1RABCG2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6182107 | 0.74 | EGFR (0.97) | EGFRCSF1RPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464375-A | ANALGESIC, ANTIINFLAMMATORY | SANKYO CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4322420-A | Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |