Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11098222 | 0.91 | CYP2D6 (0.57) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| Fumaric Acid SCHEMBL11098227 | 0.91 | CYP2D6 (0.57) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL11096422 | 0.82 | PTGS1 (0.67) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL22639907 | 0.81 | CYP2D6 (0.74) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL22640159 | 0.81 | CYP2D6 (0.74) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL10790889 | 0.81 | CYP2D6 (0.74) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL6643064 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL10774437 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11226403 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTADRB2ADRB1ADRB3 | |
| SCHEMBL11346808 | 0.80 | CYP2D6 (0.72) | CYP2D6HTTADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125315-A1 | PHENOXYAMINOPROPANOL DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-11-21 | — | — | EP | claimed |
| EP-0125315-A1 | PHENOXYAMINOPROPANOL DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-11-21 | — | — | EP | disclosed |