Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.70 |
| ▸ | PDE4A | P27815 | 2/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095055 | 1.00 | ABCG2 (0.70) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31167603 | 0.93 | ABCG2 (0.79) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2903031 | 0.87 | ABCG2 (0.62) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2903035 | 0.87 | ABCG2 (0.62) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24163300 | 0.85 | ABCG2 (0.72) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2907924 | 0.85 | ABCG2 (0.60) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2907921 | 0.85 | ABCG2 (0.60) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10991072 | 0.84 | MAPT (0.61) | ABCG2MAPTGAALMNAATM | |
| SCHEMBL9982860 | 0.82 | ABCG2 (0.86) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9982858 | 0.82 | ABCG2 (0.86) | ABCG2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483868-A | ANTIULCER AGENTS ANTISECRETORY AGENTS | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | disclosed |