SCHEMBL11095180

SCHEMBL11095180

C=C(N(C)C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25171905 0.73
SCHEMBL24160902 0.73
SCHEMBL15076112 0.73
SCHEMBL18826947 0.73
SCHEMBL18826584 0.73
SCHEMBL18408986 0.71
SCHEMBL26229226 0.71
SCHEMBL19967746 0.69
SCHEMBL24664541 0.69
SCHEMBL21180057 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226107-A1 UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US disclosed
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed
US-20230159465-A1 IMMUNOMODULATOR HITGEN INC. (CN) 2023-05-25 US disclosed
US-11466003-B2 Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) 2022-10-11 US disclosed
US-20210300916-A1 NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) 2021-09-30 US disclosed
US-20180098983-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS INTELLIKINE, INC. 2018-04-12 US disclosed
US-9771339-B2 Cystathionine-γ-lyase (CSE) inhibitors SOVA PHARMACEUTICALS, INC. (US) 2017-09-26 US disclosed
US-20170152230-A9 NOVEL COMPOUNDS FOR SELECTIVE HISTONE DEACETYLASE INHIBITORS, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2017-06-01 US disclosed
EP-0041170-B1 3-NITRO-PIVALOYL-ACETANILIDES, PROCESSES FOR THEIR PREPARATION AND THEIR UTILIZATION BAYER AG (DE) 1984-07-25 EP disclosed
EP-0041171-B1 2-CHLORO-5-NITRO-PHENYL ISOCYANATE, PROCESS FOR ITS PREPARATION AND ITS USE BAYER AG (DE) 1983-06-29 EP disclosed
US-4370499-A CHEMICAL INTERMEDIATES FOR COLOR PHOTOGRAPHY BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
EP-0041171-A1 2-Chloro-5-nitro-phenyl isocyanate, process for its preparation and its use BAYER AG (DE) 1981-12-09 EP disclosed
EP-0041170-A1 3-Nitro-pivaloyl-acetanilides, processes for their preparation and their utilization BAYER AG (DE) 1981-12-09 EP disclosed