Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL14856524 | 0.99 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11099183 | 0.89 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Ammonia Solution, Strong SCHEMBL28057253 | 0.85 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Bromide SCHEMBL28122787 | 0.81 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL3694457 | 0.81 | TSHR (0.58) | TSHRTHRBFDPSTHRAZDHHC7 | |
| SCHEMBL22318914 | 0.81 | TSHR (0.58) | TSHRTHRBFDPSTHRAZDHHC7 | |
| SCHEMBL8429135 | 0.80 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Bromide SCHEMBL3698125 | 0.80 | TSHR (0.56) | TSHRTHRBFDPSTHRAZDHHC7 | |
| Hydrochloric Acid SCHEMBL10883860 | 0.80 | TSHR (0.56) | TSHRTHRBFDPSTHRAZDHHC7 | |
| SCHEMBL17292769 | 0.80 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473813-A | CROSSLINKED SILICONE RESIN | HITACHI, LTD. (JP) | 1984-09-25 | — | — | US | disclosed |